USES OF BIOCHEMICALLITERETUREBeginningstudents of  biochemistry usuallyencounter the subject through a mixture of lectures, textbook reading  and laboratory experiments. In all of these , theideas and information are normally presented as material well established andwhich therefore, is not to be questioned but to be simply understood andmemorized. Following are the major uses of biochemical literature: LITERETURE SEARCHINGTheessence of the method is that the instructor provides the student with areference to a single paper which is known to be part of a sustained sequenceof research on a defined topic. The background of the research , the questionsit poses and their significance are discussed in class by the instructor andstudents are then required to use the biochemical literature both to trace thesubsequent development of the research up to the present time and to survey theprevious work on this specific topic. To enable students to do this , they aretaught about major abstracting and reference services available in biochemistrywith emphasis on the uses of Biological  Abstracts to follow any theme from areference paper back to earlier articles and eventually to the origins of thework as well as the use of BiologicalCitation Index to trace subsequent work on the theme up to the present day.The scope of this literature search can be limited to fit the amount of timeavailable by restricting the theme to a narrow topic or by simply following thework and progress of a single laboratory or group of scientists.

 PROGRESS AND DISCOVERYReadingthe biochemical literature and trying to develop one’s own line of inquiry ,then progressing forward in time to see how the work actually did develop andwhat answers were obtained creates a strong sense of progress and discovery. Theresult is that the student enjoys the stimulation of research and thesatisfaction of discovery without actually having to spend the effort or timeof the research worker and can have this experience long before he or she isequipped to enter the research laboratory. In the process, the student willinevitably be exposed not only to the development of information and ideas inthe chosen topic but also to the methods and approaches used. Greater or lesseremphasis may be placed upon these approaches by the instructor depending uponthe place of the topic in the course and the time available. CHOICE OF EXAMPLEAnymajor area of biochemistry may be approached in this way. Even early in a firstcourse one may successfully introduce a literature segment covering thedevelopment of amino acid sequencing in proteins. It is important inintroducing such themes that the instructor first explores the theme thoroughlyin the literature so as to chose topics which do not include concepts not yetcovered in the course , and is able to limit the topic and provide guidelinesfor the students so that the search will be fruitful and not too time-consuming.

A review which summarizes the major articles in the development of theresearch theme and which emphasizes the major advances of understanding and/or techniques in each paper should be prepared anddistributed following the completion of each segment of study to ensure thatall students have grasped the major ideas.  ANALYSING THE RESEARCHBiochemical literaturecomes in the form of systematic reviews and literaturereviews . Systematic reviews determine an objective list of criteria,and find all previously published original research papers that meet thisparticular criteria. They then compare the results presented in these papers.Literature reviews, by contrast, provide a summary of what the authors believeare the best and most relevant prior publications. The concept of review article is isolated from theconcept of peer-reviewed literature.It is possible that a review is also peer reviewed and also it is possible fora review to be non-peer-reviewed.

In this way Systemic reviews and Literaturereviews analyze or discuss the research that is previously published byscientists rather than reporting novel research results. PROVIDES CONNECTION WITHREADERBiochemicalliteraturehelps create a sort of rapport with audience or readers. As a result, they cangive you credit for your due diligence: you have done your fact-finding andfact-checking mission, one of the initial steps of any research writing.As a student, we may not bean expert in a given field; however, by listing a thorough review in researchpaper, we are telling the audience, in essence, that we know what we aretalking about. As a result, the more books, articles, and other sources we canlist in the literature review, the more trustworthy ourscholarship and expertise will be. Depending on the nature of our researchpaper, each entry can be long or short. For example, if we are writing a doctoraldissertation or thesis, the entries can be longer than the ones in a researchpaper.

The key is to stick to the sources as we synthesize the source in thereview: its thesis, research methods, findings, issues, and further discussionsmentioned in the source. HELPS AVOIDING INCIDENTAL PLAIGERISMImaginethis situation. You have written a research paper, an original paper in yourarea of expertise, without a literature review or any kind of help from varioussites. When you are about to publish the paper, you learn that someone hasalready published a paper on a topic almost similar to yours. Of course, youhave not plagiarized or copied anything from that publication; however, whenand if you publish your work, people will be suspicious of  the authenticity of your work . They will askfurther about the significance and reason behind repeating similar research.Had you prepared a literature review at the onset of your research, you couldhave easily avoided such misunderstood situation.

During the compilation ofyour work , you could have noticed how someone else has done similar work onyour topic. By knowing this fact, you can modify your own research in such away that it is not a mere copying of someone else’s original or old researchwork.  PROVIDING A SUMMARY OF RESEARCH                                                                                       By readingbiochemical literature thoroughly we can get an idea of the whole researchingprocess.

Usually the complete research is very lengthy and complicated but whenit acquires the form of literature , it not only becomes comprehensive but alsoeasily graspable . Reading literature is easy as well as time saving. Alsobiochemical literature provides a summary of research work which is useful forgaining appropriate knowledge of a certain topic.

Without biochemicalliterature , gaining knowledge would have been too difficult and timeconsuming. TO CITE THE SOURCES OF DATAScientistsrefer to the biochemical literature to point out what other work or researchhas been done on a research topic ,to cite sources of data that they use and toshow how their interpretations integrate with the published knowledge based onscience .Without biochemical literature , we could never know about the truepioneers of a research or when was that particular research published.

Biochemical literature provides us with the citations or sources of originaldata. References are specially given at the end of the research paper or anythesis which basically are citations. Each citation is given a specific numberwhich makes it easy to locate a reference. COMPARISON OF VARIOUS TOPICSBiochemicalliterature helps us compare and contrast two different or various differenttopics in the field of biochemistry. Also it helps us compare what we are doingin the historical context of research as well as how our research is differentor original from what others have done , helping us rationalize why we need todo this particular research if we are doing any. By comparison we get to knowabout other research topics alongside our own.

 ANALYSES OF BIOCHEMICAL LITERATUREAnalysesof the biochemical literature shows which journals now contribute most to thesubject and provide a guidance for librarians within a limited budget. Thejournals or papers which are too old are frequently recycled and replenishedwith new ones.    

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