Parkinson’sdisease is a neuro-degenerative disorder, leading to progressive degenerationof functions related to motor abilities of the patients due to death ofdopamine-producing brain cells.
In the initial phases of the disease, the overtsymptoms are shaking, slowness of movement, and difficulty with walking.Behavioral problems or problems in thinking may also occur. Dementia generallyoccurs in the latter stages of the disease. Depression is also common occurringin more than 33% of the people with the disease. Some other symptoms likesensory, sleep, and emotional problems may also occur. The prime motor symptomsare as a whole referred to as”parkinsonism”,or a “parkinsonian syndrome”. Patients’ voice tends to stutter andprogressively becomes affected as the disease becomes more severe.
The motor symptoms result from the deathof cells in the substantia nigra, a mid-brain region. This leads to a decreasein the amount of dopamine in these areas.The reason for this cell death is notclearly known, but includes the building up of proteins into Lewy bodies in theneurons of the brain.No cure for Parkinson’s disease exists. The treatment is just aimed atimproving the symptoms of the disease. It usually starts with the antiparkinsonmedication levodopa (L-DOPA).
As the disease progresses and neurons continue tobe lost, the medications lose their effectiveness. Moreover, they tend toproduce a complication marked by involuntary writhing movements. Diet and rehabilitationforms have exhibited some positive results at lessening symptoms. Placing microelectrodesby use of surgery for deep brain stimulation has been used to lower downsymptoms related to motor abilities incases where drugs are ineffective.
The organisation of our paper is as follows: First, weexplain the objective of our research followed by discussing the relatedprevious works in this field. Then, we describe our proposed methodology andthe experimentation work. Finally, we conclude with accuracy and data analysisresults and future scope of our research which could further better the output.