disease is a neuro-degenerative disorder, leading to progressive degeneration
of functions related to motor abilities of the patients due to death of
dopamine-producing brain cells. In the initial phases of the disease, the overt
symptoms are shaking, slowness of movement, and difficulty with walking.
Behavioral problems or problems in thinking may also occur. Dementia generally
occurs in the latter stages of the disease. Depression is also common occurring
in more than 33% of the people with the disease. Some other symptoms like
sensory, sleep, and emotional problems may also occur. The prime motor symptoms
are as a whole referred to as”parkinsonism”,
or a “parkinsonian syndrome”. Patients’ voice tends to stutter and
progressively becomes affected as the disease becomes more severe.
The motor symptoms result from the death
of cells in the substantia nigra, a mid-brain region. This leads to a decrease
in the amount of dopamine in these areas.The reason for this cell death is not
clearly known, but includes the building up of proteins into Lewy bodies in the
neurons of the brain.
No cure for Parkinson’s disease exists. The treatment is just aimed at
improving the symptoms of the disease. It usually starts with the antiparkinson
medication levodopa (L-DOPA). As the disease progresses and neurons continue to
be lost, the medications lose their effectiveness. Moreover, they tend to
produce a complication marked by involuntary writhing movements. Diet and rehabilitation
forms have exhibited some positive results at lessening symptoms. Placing microelectrodes
by use of surgery for deep brain stimulation has been used to lower down
symptoms related to motor abilities in
cases where drugs are ineffective.
The organisation of our paper is as follows: First, we
explain the objective of our research followed by discussing the related
previous works in this field. Then, we describe our proposed methodology and
the experimentation work. Finally, we conclude with accuracy and data analysis
results and future scope of our research which could further better the output.