Obsessive-Compulsive Disorder (OCD) is a common,chronic and long-lasting disorder in which a person has uncontrollable,reoccurring thoughts (obsessions) and behaviours (compulsions)that he or she feels the urge to repeat over and over1.
Pharmacological and psychologicaltreatments are the two most widely used treatments approaches2.Clomipramine was the first agent found to have efficacy in OCD .The drug shares the pharmacological properties of thetricyclic group of antidepressants from which it is derived 3.
Theantidepressant effects of clomipramine are thought to be due to reuptakeinhibition of serotonin and norepinephrine while serotonin reuptake inhibition only isbelieved to be responsible for the effectiveness of clomipramine in thetreatment of OCD4. SSRIs are generally preferred over clomipramine intreating OCD. The adverse effect profiles of SSRIs are less, so improvedcompliance is observed. Available SSRIs include fluoxetine (Prozac),fluvoxamine (Luvox), paroxetine (Paxil), citalopram (Celexa), escitalopram(Lexapro), and sertraline (Zoloft)5.
Despite the provenefficacy of SSRIs and clomipramine in OCD, many patients show no or just partial symptom improvement to a treatmentwith a first-line drug. The combination of the antipsychotics risperidone,haloperidol, olanzapine, or quetiapine with an SSRI was shown to be moreeffective than SSRI monotherapy in such cases and is recommended by the WFSBP World Federation of Societies ofBiological Psychiatryguidelines6.Prescribing a suitablemedication for a particular patient is done on the basis of many factorsincluding patient’s demographic characteristics, illness profile, side effectsof the medication, co morbidities. So, analysis of prescription patternscan help in identifying prevalent practices of the use of medications in reallife7.
The concept of QOL is often considered a missingmeasurement in healthcare. Inquiry into QOL proved to be useful because manystudies in the recent time showed correlations between QOL and distress thatoften leads to worsening of symptomssuch as those of OCD. Hence, the aim of the present study was to assess and quantifyQOL in patients suffering from OCD8.Today, in an age where health care is scrutinized, notonly for the quality of that which we provide but also the satisfaction ofthose who receive it.
Patient satisfaction along with the health care providedby doctors is of great medical significance. Thus, it is important to find out weaknesses in systems to aid improvementthrough the patient’s eyes9.