Obesity can disrupt human function. 
One of the most prevalent topics discussed is how obesity effects
metabolic changes.  Metabolic change
consist of the buildup and breakdown of substances that are used for energy.  Metabolic deformities of obesity reflect
molecular signals originating from the increase mass of fat cells.  Although metabolic syndrome is not a disease,
it is a cluster of disorders of your body’s metabolism, including: high blood
pressure, high insulin levels, excess body weight, and abnormal cholesterol levels.  Each of these disorders in itself is a risk
factor for other diseases. Life-threatening illnesses, such as diabetes, heart
disease or a stroke can develop if their happens to be a combination of
disorders.  Metabolic syndrome is linked
to a metabolic disorder called insulin resistance, which make it hard for the body
to use insulin sufficiently.  Risk
factors that can increase the risk of developing Metabolic Syndrome include:
age, race, obesity, history of diabetes, and other diseases.  Over the past decade Metabolic Syndrome has increased
by sixty-one percent.  Adults over the
age of forty are affected more than forty percent.  Obesity also affects hormones
leptin and insulin, and growth hormone influence our appetite, metabolism, and
fat distribution.  The endocrine system
is made up of a system of different glands that secretes our hormones into our bloodstream.  The endocrine system
also works with the nervous and immune systems, to help our body cope with
different situations and anxieties. 
Obesity can lead to changes in hormones. 
Leptin is a hormone that is produced by fat cells, which helps a person’s
appetite by triggering the brain to reduce the urge to eat.  Leptin also controls how our body fat is
managed.  Since
leptin is produced by fat, its levels tend to be higher in people who are obese
then people of normal weight.  Insulin
is a hormone that is produced by the pancreas, which is important for managing carbohydrate
intake and the metabolism of fat.  The
muscles, liver, and fat are stimulated by insulin and glucose intake.  This process is important to make sure normal
levels of circulating glucose is available. 
Insulin signals in an obese person are sometimes no longer able to
control glucose levels.  In this case the
development of type II diabetes or metabolic syndrome can occur.  Growth hormones are produced in the pituitary
gland.  This gland effects a person’s height
and helps build bone and muscle.  Growth
hormones also affects metabolism rate.  Researchers
found that growth hormone levels in obese people are lower in people of normal
weight.  The hormones leptin, insulin,
and growth hormone influences our appetite, metabolism and body fat


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