Obesity can disrupt human function. One of the most prevalent topics discussed is how obesity effectsmetabolic changes.

  Metabolic changeconsist of the buildup and breakdown of substances that are used for energy.  Metabolic deformities of obesity reflectmolecular signals originating from the increase mass of fat cells.  Although metabolic syndrome is not a disease,it is a cluster of disorders of your body’s metabolism, including: high bloodpressure, high insulin levels, excess body weight, and abnormal cholesterol levels.

  Each of these disorders in itself is a riskfactor for other diseases. Life-threatening illnesses, such as diabetes, heartdisease or a stroke can develop if their happens to be a combination ofdisorders.  Metabolic syndrome is linkedto a metabolic disorder called insulin resistance, which make it hard for the bodyto use insulin sufficiently.

  Riskfactors that can increase the risk of developing Metabolic Syndrome include:age, race, obesity, history of diabetes, and other diseases.  Over the past decade Metabolic Syndrome has increasedby sixty-one percent.  Adults over theage of forty are affected more than forty percent.  Obesity also affects hormonesleptin and insulin, and growth hormone influence our appetite, metabolism, andfat distribution.  The endocrine systemis made up of a system of different glands that secretes our hormones into our bloodstream.  The endocrine systemalso works with the nervous and immune systems, to help our body cope withdifferent situations and anxieties. Obesity can lead to changes in hormones. Leptin is a hormone that is produced by fat cells, which helps a person’sappetite by triggering the brain to reduce the urge to eat.

  Leptin also controls how our body fat ismanaged.  Sinceleptin is produced by fat, its levels tend to be higher in people who are obesethen people of normal weight.  Insulinis a hormone that is produced by the pancreas, which is important for managing carbohydrateintake and the metabolism of fat.  Themuscles, liver, and fat are stimulated by insulin and glucose intake.

  This process is important to make sure normallevels of circulating glucose is available. Insulin signals in an obese person are sometimes no longer able tocontrol glucose levels.  In this case thedevelopment of type II diabetes or metabolic syndrome can occur.  Growth hormones are produced in the pituitarygland.  This gland effects a person’s heightand helps build bone and muscle.

  Growthhormones also affects metabolism rate.  Researchersfound that growth hormone levels in obese people are lower in people of normalweight.  The hormones leptin, insulin,and growth hormone influences our appetite, metabolism and body fatdistribution 


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